Autologous perichondral tissue for meniscal replacement

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Autologous perichondral tissue for meniscal replacement.

Our aim was to examine the potential of autologous perichondral tissue to form a meniscal replacement. In 18 mature sheep we performed a complete medial meniscectomy. The animals were then divided into two groups: 12 had a meniscal replacement using strips of autologous perichondral tissue explanted from the lower rib (group G) and six (group C) served as a control group without a meniscal repl...

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Surgical options for meniscal replacement.

As a result of biologic issues and technical limitations, repair of the meniscus is indicated for unstable, peripheral vertical tears; most other types of meniscal tears that are degenerative, significantly traumatized, and/or located in an avascular area of the meniscus are managed with partial meniscectomy. Options to restore the meniscus range from allograft transplantation to the use of syn...

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Percutaneous pulmonary valve replacement: autologous tissue-engineered valved stents.

AIMS Percutaneous implantation has already been used clinically and is a great option for treating young patients. The use of autologous tissue-engineered valved stents might solve the problem of degeneration and limited durability of biological heart valves. METHODS AND RESULTS Porcine pulmonary heart valves and small intestinal submucosa were obtained from a slaughterhouse. The intestinal s...

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Advances in Meniscal Tissue Engineering

Meniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. Preliminary studies did not all...

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Advances in meniscal tissue engineering.

Injuries and lesions to the meniscal cartilage of the knee joint are common. As a result of its limited regenerative capacity, early degenerative changes to the articular surface frequently occur, resulting in pain and poor function. Currently available surgical interventions include repair of tears, and partial and total meniscectomy but the results are inconsistent and often poor. Interest in...

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ژورنال

عنوان ژورنال: The Journal of Bone and Joint Surgery. British volume

سال: 1998

ISSN: 0301-620X,2044-5377

DOI: 10.1302/0301-620x.80b5.0800918